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DNA Replication Licensing Factor MCM2 (MCM2) Antibody

Catalogue No: abx000979
Price: £120.00
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DNA Replication Licensing Factor MCM2 (MCM2) Antibody

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MCM2 Antibody is a Rabbit Polyclonal antibody against MCM2. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Target MCM2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MCM2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49736 (UniProt, ExPASy)
UniProt Secondary AC Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7
UniProt Entry Name MCM2_HUMAN
Gene Symbol MCM2
GeneID 4171
KEGG hsa:417
String 9606.ENSP00000265056
Molecular Weight Calculated MW: 101 kDa
Observed MW: 130 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Replication Licensing Factor MCM2 (MCM2) Antibody

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