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Minichromosome Maintenance Deficient 3 (MCM3) Antibody

Catalogue No: abx000983
Price: £120.00
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Minichromosome Maintenance Deficient 3 (MCM3) Antibody Minichromosome Maintenance Deficient 3 (MCM3) Antibody

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MCM3 Antibody is a Rabbit Polyclonal antibody against MCM3. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Target MCM3
Clonality Polyclonal
Reactivity Human, Mouse, Monkey
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MCM3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P25205 (UniProt, ExPASy)
UniProt Secondary AC B4DWW4, Q92660, Q9BTR3, Q9NUE7
UniProt Entry Name MCM3_HUMAN
Gene Symbol MCM3
GeneID 4172
String 9606.ENSP00000480987
Molecular Weight Calculated MW: 90 kDa, 95 kDa
Observed MW: 115 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Minichromosome Maintenance Deficient 3 (MCM3) Antibody

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