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Minichromosome Maintenance Deficient 7 (MCM7) Antibody

Catalogue No: abx001052
Price: £120.00
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Minichromosome Maintenance Deficient 7 (MCM7) Antibody

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MCM7 Antibody is a Rabbit Polyclonal antibody against MCM7. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Target MCM7
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MCM7.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P33993 (UniProt, ExPASy)
UniProt Secondary AC A4D2A1, A4D2A2, E9PGN9, Q15076, Q96D34, Q96GL1
UniProt Entry Name MCM7_HUMAN
Gene Symbol MCM7
GeneID 4176
String 9606.ENSP00000307288
Molecular Weight Calculated MW: 44 kDa, 60 kDa, 81 kDa
Observed MW: 81 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Minichromosome Maintenance Deficient 7 (MCM7) Antibody

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