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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody

Catalogue No: abx000690
Price: £95.00
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Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody Mdm2 p53 Binding Protein Homolog (MDM2) Antibody

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MDM2 Antibody is a Rabbit Polyclonal antibody against MDM2. This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Target MDM2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MDM2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UNSPSC Code 12352203
UniProt Primary AC Q00987
Gene Symbol MDM2
GeneID 4193
Molecular Weight Calculated MW: 11-14 kDa, 24-55 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mdm2 p53 Binding Protein Homolog (MDM2) Antibody

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