Mdm2 p53 Binding Protein Homolog Phospho-Ser260 (MDM2 pS260) Antibody

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Catalogue No: abx000147
Price: US$232.00
(Size: 20 µl)

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Datasheet SDS
MDM2 (pS260) Antibody is a Rabbit Polyclonal antibody against MDM2 (pS260). This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Target Mdm2 p53 Binding Protein Homolog Phospho-Ser260 (MDM2 pS260)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic phosphorylated peptide around S260 of human MDM2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q00987 (UniProt, ExPASy)
Gene Symbol MDM2
GeneID 4193
NCBI Accession NP_001354919.1
Molecular Weight Calculated MW: 55 kDa
Observed MW: 95 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mdm2 p53 Binding Protein Homolog Phospho-Ser260 (MDM2 pS260)


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