Me2-H4 Antibody
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Catalogue No: abx032069
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.
Research Articles on Me2-H4
| Target | Me2-H4 |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM, DB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from human H4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step methylation specific peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P62805 (UniProt, ExPASy) |
| UniProt Secondary AC | A2VCL0, P02304, P02305, Q6DRA9, Q6FGB8, Q6NWP7 |
| UniProt Entry Name | H4_HUMAN |
| KEGG | hsa:121504 hsa:554313 hsa:8294 hsa:8359 hsa:8360 hsa:8361 hsa:8362 hsa:8363 hsa:8364 hsa:8365 hsa:8366 hsa:8367 hsa:8368 hsa:8370 |
| String | 9606.ENSP00000484789 |
| Molecular Weight | Calculated MW: 11.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |