Mediator Complex Subunit 1 (MED1) Antibody

MED1 Antibody is a Rabbit Polyclonal antibody against MED1. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008].

Target	Mediator Complex Subunit 1 (MED1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MED1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15648 (UniProt, ExPASy)
UniProt Secondary AC	A2RRQ6, O43810, O75447, Q6P9H7, Q6PK58, Q9HD39
UniProt Entry Name	MED1_HUMAN
Gene Symbol	MED1
GeneID	5469
NCBI Accession	NP_004765.2
KEGG	hsa:5469
String	9606.ENSP00000300651
Molecular Weight	Calculated MW: 168 kDa Observed MW: 250 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mediator Complex Subunit 1 (MED1)

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