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Mediator Complex Subunit 1 (MED1) Antibody

Catalogue No: abx001441
Price: £120.00
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Mediator Complex Subunit 1 (MED1) Antibody

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MED1 Antibody is a Rabbit Polyclonal antibody against MED1. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008].

Target Mediator complex subunit 1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MED1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15648 (UniProt, ExPASy)
UniProt Secondary AC A2RRQ6, O43810, O75447, Q6P9H7, Q6PK58, Q9HD39
UniProt Entry Name MED1_HUMAN
Gene Symbol MED1
GeneID 5469
KEGG hsa:5469
String 9606.ENSP00000300651
Molecular Weight Calculated MW: 61 kDa, 168 kDa
Observed MW: 160 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mediator Complex Subunit 1 (MED1) Antibody

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