Mediator Complex Subunit 1 (MED1) Antibody
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Catalogue No: abx001441
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US$217.50
(Size: 20 µl)
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Datasheet SDS
MED1 Antibody is a Rabbit Polyclonal antibody against MED1. The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008].
Research Articles on Mediator Complex Subunit 1 (MED1)
| Target | Mediator Complex Subunit 1 (MED1) |
| Research Area | Endocrinology, Developmental Science, Hormone Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MED1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15648 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RRQ6, O43810, O75447, Q6P9H7, Q6PK58, Q9HD39 |
| UniProt Entry Name | MED1_HUMAN |
| Gene Symbol | MED1 |
| GeneID | 5469 |
| NCBI Accession | NP_004765.2 |
| KEGG | hsa:5469 |
| String | 9606.ENSP00000300651 |
| Molecular Weight | Calculated MW: 168 kDa Observed MW: 250 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |