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Mediator of RNA Polymerase II Transcription Subunit 7 (MED7) Antibody
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Catalogue No: abx026530
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Research Articles on Mediator of RNA Polymerase II Transcription Subunit 7 (MED7)
| Target | Mediator of RNA Polymerase II Transcription Subunit 7 (MED7) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 83-111 amino acids from the Central region of human MED7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43513 (UniProt, ExPASy) |
| UniProt Entry Name | MED7_HUMAN |
| Gene Symbol | MED7 |
| KEGG | hsa:9443 |
| String | 9606.ENSP00000286317 |
| Molecular Weight | Calculated MW: 27.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Cow and Pig MED7. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |