MEK1 (pS222) Antibody

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Catalogue No: abx032048
Price: US$326.25
(Size: 80 µl)

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Documents

Datasheet SDS
MEK1is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.

Target MEK1 (pS222)
Clonality Polyclonal
Target Modification Ser222
Modification Phosphorylation
Reactivity Human
Tested Applications ELISA, WB, DB
Host Rabbit
Recommended dilutions WB: 1/500, DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S222 of human MEK1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q02750 (UniProt, ExPASy)
UniProt Entry Name MP2K1_HUMAN
NCBI Accession NP_002746.1
KEGG hsa:5604
String 9606.ENSP00000302486
Molecular Weight Calculated MW: 43.4 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat, Hamster, Drosophila and Xenopus MAP2K1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MEK1 (pS222)


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