Mesoderm Posterior BHLH Transcription Factor 2 (MESP2) Antibody

This gene encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. This gene is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. This gene also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).

Target	Mesoderm Posterior BHLH Transcription Factor 2 (MESP2)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human MESP2 (AA: 37-94) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q0VG99 (UniProt, ExPASy)
UniProt Secondary AC	Q7RTU2
UniProt Entry Name	MESP2_HUMAN
Gene Symbol	MESP2
GeneID	145873
OMIM	605195
HGNC	29659
KEGG	hsa:145873
Ensembl	ENSG00000188095
String	9606.ENSP00000342392
Molecular Weight	41.8 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mesoderm Posterior BHLH Transcription Factor 2 (MESP2)

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