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Methylenetetrahydrofolate Reductase (MTHFR) Antibody
Catalogue No: abx000043
Price:
£120.00
(Size: 20 µl)
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MTHFR Antibody is a Mouse Polyclonal antibody against MTHFR. The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Research Articles on MTHFR
| Target | MTHFR |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | WB, IHC |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human MTHFR. |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6P5Z2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UM03 |
| UniProt Entry Name | PKN3_HUMAN |
| GeneID | 4524 |
| KEGG | hsa:29941 |
| String | 9606.ENSP00000291906 |
| Molecular Weight | 56 kDa |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| Concentration | > 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
