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Methylenetetrahydrofolate Reductase (MTHFR) Antibody
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Catalogue No: abx000043
Price:
US$217.50
(Size: 20 µl)
Orders to United States ship from United States
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MTHFR Antibody is a Mouse Polyclonal antibody against MTHFR. The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Research Articles on Methylenetetrahydrofolate Reductase (MTHFR)
| Target | Methylenetetrahydrofolate Reductase (MTHFR) |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to MTHFR. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6P5Z2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9UM03 |
| UniProt Entry Name | PKN3_HUMAN |
| GeneID | 4524 |
| NCBI Accession | NP_005948.3 |
| KEGG | hsa:29941 |
| String | 9606.ENSP00000291906 |
| Molecular Weight | Calculated MW: 75 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |