Microtubule-Associated Protein Tau (MAPT) Antibody

Microtubule-Associated Protein Tau (MAPT) Antibody is a rabbit monoclonal antibody against Microtubule-Associated Protein Tau (MAPT). This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008].

Target	Microtubule-Associated Protein Tau (MAPT)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, IF/ICC, DB
Host	Rabbit
Recommended dilutions	WB: 1/500, IHC: 1/500, IF/ICC: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthetic peptide of Human Phospho Tau (Ser202/Thr205).
Isotype	IgG
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P10636 (UniProt, ExPASy)
UniProt Secondary AC	P18518, Q14799, Q15549, Q15550, Q15551, Q1RMF6, Q53YB1, Q5CZI7, Q5XWF0, Q6QT54, Q9UDJ3, Q9UMH0, Q9UQ96
UniProt Entry Name	TAU_HUMAN
Gene Symbol	MAPT
GeneID	4137
OMIM	157140
HGNC	6893
KEGG	hsa:4137
String	9606.ENSP00000340820
Buffer	PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Specificity	Detects ~79 kDa.
Concentration	1 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Microtubule-Associated Protein Tau (MAPT)

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