Melanogenesis Associated Transcription Factor (MITF) Antibody
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Catalogue No: abx001164
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US$348.00
(Size: 60 µl)
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Datasheet SDS
MITF Antibody is a Rabbit Polyclonal antibody against MITF. This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Research Articles on Melanogenesis Associated Transcription Factor (MITF)
| Target | Melanogenesis Associated Transcription Factor (MITF) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human MITF |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75030 (UniProt, ExPASy) |
| UniProt Entry Name | MITF_HUMAN |
| Gene Symbol | MITF |
| GeneID | 4286 |
| NCBI Accession | NP_937801.1 |
| KEGG | hsa:4286 |
| String | 9606.ENSP00000295600 |
| Molecular Weight | Calculated MW: 40 kDa/46 kDa/52 kDa/55 kDa/56 kDa/57 kDa/58 kDa Observed MW: 65 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
