Mitogen-Activated Protein Kinase 14 (MAPK14) Antibody

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Catalogue No: abx015918
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
The protein encoded by this gene is a member of the MAP kinase family.MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.This kinase is activated by various environmental stresses and proinflammatory cytokines.The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase.The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Target Mitogen-Activated Protein Kinase 14 (MAPK14)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/75, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human MAPK14 (AA: 299-360) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID 1432 26416
Molecular Weight 41.3 kDa
Buffer PBS, containing 0.05% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mitogen-Activated Protein Kinase 14 (MAPK14)


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