Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3) Antibody
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Catalogue No: abx147064
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3) Antibody is a Rabbit Polyclonal antibody for the detection of ERK1. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Research Articles on Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3)
| Target | Mitogen-Activated Protein Kinase 3 / ERK1 (MAPK3) |
| Research Area | Signal Transduction, Enzymes and Kinases, Apoptosis, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | mitogen-activated protein kinase 3 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P27361 (UniProt, ExPASy) |
| UniProt Secondary AC | A8CZ58, B0LPG3, Q8NHX1 |
| UniProt Entry Name | MK03_HUMAN |
| Gene Symbol | MAPK3 |
| GeneID | 5595 |
| OMIM | 601795 |
| HGNC | 6877 |
| KEGG | hsa:5595 |
| Ensembl | ENSG00000102882 |
| String | 9606.ENSP00000263025 |
| Molecular Weight | Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |