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DNA Mismatch Repair Protein Mlh1 (MLH1) Antibody
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Catalogue No: abx012221
Price:
US$427.75
(Size: 100 µl)
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This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Research Articles on DNA Mismatch Repair Protein Mlh1 (MLH1)
| Target | DNA Mismatch Repair Protein Mlh1 (MLH1) |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of MLH1 (aa381-483) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P40692 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DI13, B4DQ11, E9PCU2 |
| UniProt Entry Name | MLH1_HUMAN |
| Gene Symbol | MLH1 |
| GeneID | 4292 |
| OMIM | 114500 |
| NCBI Accession | NP_000240.1 NM_000249.3 |
| HGNC | 7127 |
| KEGG | hsa:4292 |
| Ensembl | ENSG00000076242 |
| String | 9606.ENSP00000231790 |
| Molecular Weight | 85 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |