Matrix Metalloproteinase 1 (MMP1) Antibody

MMP1 Antibody is a Rabbit Polyclonal antibody against MMP1. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].

Target	Matrix Metalloproteinase 1 (MMP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human MMP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P03956 (UniProt, ExPASy)
UniProt Secondary AC	P08156
UniProt Entry Name	MMP1_HUMAN
Gene Symbol	MMP1
GeneID	4312
NCBI Accession	NP_002412.1
KEGG	hsa:4312
String	9606.ENSP00000322788
Molecular Weight	Calculated MW: 54 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Matrix Metalloproteinase 1 (MMP1)

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