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Matrix Metalloproteinase 11 (MMP11) Antibody

Catalogue No: abx002195
Price: £120.00
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Matrix Metalloproteinase 11 (MMP11) Antibody

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MMP11 Antibody is a Rabbit Polyclonal antibody against MMP11. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Target Matrix Metalloproteinase 11 (MMP11)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human MMP11.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P24347 (UniProt, ExPASy)
UniProt Secondary AC Q5FX24, Q6PEZ6, Q9UC26
UniProt Entry Name MMP11_HUMAN
Gene Symbol MMP11
GeneID 4320
KEGG hsa:4320
String 9606.ENSP00000215743
Enzyme Commission Number EC 3.4.24.24 EC 3.4.24.- EC 3.4.24
Molecular Weight Calculated MW: 54 kDa
Observed MW: 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Matrix Metalloproteinase 11 (MMP11) Antibody

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