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Matrix Metalloproteinase 14 (MMP14) Antibody

Catalogue No: abx001987
Price: £120.00
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Matrix Metalloproteinase 14 (MMP14) Antibody Matrix Metalloproteinase 14 (MMP14) Antibody Matrix Metalloproteinase 14 (MMP14) Antibody Matrix Metalloproteinase 14 (MMP14) Antibody Matrix Metalloproteinase 14 (MMP14) Antibody

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MMP14 Antibody is a Rabbit Polyclonal antibody against MMP14. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Target Matrix Metalloproteinase 14 (MMP14)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MMP14.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P50281 (UniProt, ExPASy)
UniProt Secondary AC A8K5L0, Q6GSF3, Q92678
UniProt Entry Name MMP14_HUMAN
Gene Symbol MMP14
GeneID 4323
KEGG hsa:4323
String 9606.ENSP00000308208
Molecular Weight Calculated MW: 65 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Matrix Metalloproteinase 14 (MMP14) Antibody

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