Matrix Metalloproteinase-16 (MMP16) Antibody
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Catalogue No: abx027555
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Research Articles on Matrix Metalloproteinase-16 (MMP16)
| Target | Matrix Metalloproteinase-16 (MMP16) |
| Research Area | Enzymes and Kinases, Metabolic Pathways, Tumor Immunity, Infection Immunity, Hepatology, Rheumatology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human MMP16. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P51512 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAN7, Q14824, Q52H48 |
| UniProt Entry Name | MMP16_HUMAN |
| KEGG | hsa:4325 |
| String | 9606.ENSP00000286614 |
| Molecular Weight | Calculated MW: 69.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |