Matrix Metalloproteinase 20 (MMP20) Antibody
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Catalogue No: abx027674
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and so the protein is thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes that localizes to chromosome 11q22.3.
Research Articles on Matrix Metalloproteinase 20 (MMP20)
| Target | Matrix Metalloproteinase 20 (MMP20) |
| Research Area | Enzymes and Kinases, Hematology, Reproductive Science, Developmental Science |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 399-428 amino acids from the C-terminal region of human MMP20. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O60882 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6DKT9 |
| UniProt Entry Name | MMP20_HUMAN |
| Gene Symbol | MMP20 |
| KEGG | hsa:9313 |
| String | 9606.ENSP00000260228 |
| Molecular Weight | Calculated MW: 54.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow MMP20. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |