Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3) Antibody

Catalogue No: abx001114
Price: £120.00
(Size: 20 µl)
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MMP3 Antibody is a Rabbit Polyclonal antibody against MMP3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].

Target Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MMP3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P08254 (UniProt, ExPASy)
UniProt Secondary AC B2R8B8, Q3B7S0, Q6GRF8
UniProt Entry Name MMP3_HUMAN
Gene Symbol MMP3
GeneID 4314
KEGG hsa:4314
String 9606.ENSP00000299855
Enzyme Commission Number EC 3.4.24.17 EC 3.4.24
Molecular Weight Calculated MW: 53 kDa
Observed MW: 54 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3)

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