Matrix Metalloproteinase-9 (MMP9) Antibody
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Catalogue No: abx011175
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US$449.50
(Size: 100 µl)
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Datasheet SDS
MMP9 antibody detects endogenous levels of total MMP9. MMP9 May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family. Activated by 4-aminophenylmercuric acetate and phorbol ester. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.
Research Articles on Matrix Metalloproteinase-9 (MMP9)
| Target | Matrix Metalloproteinase-9 (MMP9) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Infection Immunity, Cardiovascular Biology, Hepatology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthesised peptide derived from human MMP9 |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P14780 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7V9, Q3LR70, Q8N725, Q9H4Z1, Q9UCJ9, Q9UCL1, Q9UDK2 |
| UniProt Entry Name | MMP9_HUMAN |
| Gene Symbol | MMP9 |
| KEGG | hsa:4318 |
| Ensembl | ENSG00000100985 |
| String | 9606.ENSP00000361405 |
| Enzyme Commission Number | EC 3.4.24.35 EC 3.4.24 |
| Molecular Weight | 78 kDa |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Specificity | MMP9 antibody detects endogenous levels of total MMP9 |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |