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| Target | MCP 2 |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Biological Activity | The biological activity was determined by measuring the dose dependent mobilization of intracellular calcium (calcium flux) with human THP-1 cells. Significant calcium mobilization is observed with 5ng/mL of recombinant human MCP-2. Human MCP-2 also induces dose dependent chemotaxis of human THP-1 cells with an ED5=3-1 ng/mL corresponding to a Specific Activity of 1,-33,334IU/mg. |
| Purity | > 95% (SDS-PAGE and RP-HPLC) |
| Reconstitution | It is recommended to reconstitute the lyophilized Monocyte Chemotactic Protein-2in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage | Store lyophilized at -18°C for long term storage. It is recommended to add a carrier protein (0.1% HSA or BSA). Upon reconstitution, store at 4°C for up to 1 week. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P80075 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AV77, P78388 |
| UniProt Entry Name | CCL8_HUMAN |
| KEGG | hsa:6355 |
| String | 9606.ENSP00000378118 |
| Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Asp-Ser-Val. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |