Mitogen-Activated Protein Kinase 14 (MAPK14) Antibody

Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Also plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression.

Target	Mitogen-Activated Protein Kinase 14 (MAPK14)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 26-53 amino acids from the N-terminal region of mouse Mapk14.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P47811 (UniProt, ExPASy)
UniProt Entry Name	MK14_MOUSE
KEGG	mmu:26416
String	10090.ENSMUSP00000004990
Molecular Weight	Calculated MW: 41.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat Mapk14.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mitogen-Activated Protein Kinase 14 (MAPK14)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue