+44 (0) 1223 755950
+1 832 327 7413
Membrane-Associated Tyrosine- And Threonine-Specific Cdc2-Inhibitory Kinase (Pkmyt1) Antibody
REQUEST MORE INFO
Catalogue No: abx027787
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Pkmyt1 acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity).
Research Articles on Membrane-Associated Tyrosine- And Threonine-Specific Cdc2-Inhibitory Kinase (Pkmyt1)
| Target | Membrane-Associated Tyrosine- And Threonine-Specific Cdc2-Inhibitory Kinase (Pkmyt1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of mouse Pkmyt1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9ESG9 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3TNN2, Q8R3L4 |
| UniProt Entry Name | PMYT1_MOUSE |
| String | 10090.ENSMUSP00000024701 |
| Molecular Weight | Calculated MW: 54.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |