Serine/threonine-Protein Kinase TBK1 (Tbk1) Antibody
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Catalogue No: abx029446
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.
Research Articles on Serine/threonine-Protein Kinase TBK1 (Tbk1)
| Target | Serine/threonine-Protein Kinase TBK1 (Tbk1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9WUN2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9CT90, Q9DC03 |
| UniProt Entry Name | TBK1_MOUSE |
| String | 10090.ENSMUSP00000020316 |
| Molecular Weight | Calculated MW: 83.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |