Mouse TUG Antibody

The TUG protein contains a UBX domain, for GLUT4.In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes.Full-length TUG forms a complex specifically with GLUT4.In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin.Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

Target	Mouse TUG
Clonality	Monoclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of TUG expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	79058
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mouse TUG

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