Mouse Txnip Antibody

May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.

Target	Mouse Txnip
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/2000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8BG60 (UniProt, ExPASy)
UniProt Secondary AC	Q8BGQ0, Q8K2B2, Q9DC00, Q9EP90, Q9R115
UniProt Entry Name	TXNIP_MOUSE
KEGG	mmu:56338
String	10090.ENSMUSP00000102710
Molecular Weight	Calculated MW: 44.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat Txnip.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Mouse Txnip

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