Chromosome 20 Open Reading Frame 20 (MRGBP) Antibody

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Target	Chromosome 20 Open Reading Frame 20 (MRGBP)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 46-75 amino acids from the Central region of human MRGBP.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NV56 (UniProt, ExPASy)
UniProt Secondary AC	A8C4L5
UniProt Entry Name	MRGBP_HUMAN
Gene Symbol	MRGBP
String	9606.ENSP00000359518
Molecular Weight	Calculated MW: 22.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse MRGBP.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chromosome 20 Open Reading Frame 20 (MRGBP)

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