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DNA Mismatch Repair Protein Msh2 (MSH2) Antibody
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Catalogue No: abx011203
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
Research Articles on DNA Mismatch Repair Protein Msh2 (MSH2)
| Target | DNA Mismatch Repair Protein Msh2 (MSH2) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MSH2 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P43246 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E2Z2, O75488 |
| UniProt Entry Name | MSH2_HUMAN |
| Gene Symbol | MSH2 |
| GeneID | 4436 |
| OMIM | 114500 |
| NCBI Accession | NP_000242.1 NM_000251.2 |
| HGNC | 7325 |
| KEGG | hsa:4436 |
| Ensembl | ENSG00000095002 |
| String | 9606.ENSP00000233146 |
| Molecular Weight | 105 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |