DNA Mismatch Repair Protein Msh2 (MSH2) Antibody

Catalogue No: abx000543
Price: £270.00
(Size: 100 µl)
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MSH2 Antibody is a Rabbit Polyclonal antibody against MSH2. This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Target MSH2
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human MSH2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P43246 (UniProt, ExPASy)
UniProt Secondary AC B4E2Z2, O75488
UniProt Entry Name MSH2_HUMAN
Gene Symbol MSH2
GeneID 4436
KEGG hsa:4436
String 9606.ENSP00000233146
Molecular Weight Calculated MW: 97 kDa, 104 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MSH2

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