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DNA Mismatch Repair Protein Msh2 (MSH2) Antibody
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Catalogue No: abx000543
Price:
US$203.00
(Size: 20 µl)
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MSH2 Antibody is a Rabbit Polyclonal antibody against MSH2. This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on DNA Mismatch Repair Protein Msh2 (MSH2)
| Target | DNA Mismatch Repair Protein Msh2 (MSH2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43246 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E2Z2, O75488 |
| UniProt Entry Name | MSH2_HUMAN |
| Gene Symbol | MSH2 |
| GeneID | 4436 |
| OMIM | 114500 |
| NCBI Accession | NP_000242.1 NM_000251.2 |
| HGNC | 7325 |
| KEGG | hsa:4436 |
| Ensembl | ENSG00000095002 |
| String | 9606.ENSP00000233146 |
| Molecular Weight | Calculated MW: 105 kDa Observed MW: 150 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
