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DNA Mismatch Repair Protein Msh2 (MSH2) Antibody

Catalogue No: abx000543
Price: £270.00
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Western blot analysis of extracts of HeLa cells, using MSH2 antibody (abx000543).
DNA Mismatch Repair Protein Msh2 (MSH2) Antibody

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MSH2 Antibody is a Rabbit Polyclonal antibody against MSH2. This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Target MSH2
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human MSH2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P43246 (UniProt, ExPASy)
UniProt Secondary AC B4E2Z2, O75488
UniProt Entry Name MSH2_HUMAN
Gene Symbol MSH2
GeneID 4436
KEGG hsa:4436
String 9606.ENSP00000233146
Molecular Weight Calculated MW: 97 kDa, 104 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA Mismatch Repair Protein Msh2 (MSH2) Antibody

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