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DNA Mismatch Repair Protein Msh2 (MSH2) Antibody
Catalogue No: abx000543
Price:
£270.00
(Size: 100 µl)
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MSH2 Antibody is a Rabbit Polyclonal antibody against MSH2. This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on MSH2
| Target | MSH2 |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein of human MSH2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| UniProt Primary AC | P43246 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E2Z2, O75488 |
| UniProt Entry Name | MSH2_HUMAN |
| Gene Symbol | MSH2 |
| GeneID | 4436 |
| KEGG | hsa:4436 |
| String | 9606.ENSP00000233146 |
| Molecular Weight | Calculated MW: 97 kDa, 104 kDa Observed MW: 100 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
