G/T Mismatch-Binding Protein (MSH6) Antibody

Catalogue No: abx015932
Price: £290.00
(Size: 100 µl)

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Datasheet SDS
This gene encodes a protein similar to the MutS protein.In E.coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair.A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs.The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated.Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.

Target MSH6
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human MSH6 expressed in E. coli.
Isotype IgG2a
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P52701 (UniProt, ExPASy)
UniProt Secondary AC B4DF41, B4E3I4, F5H2F9, O43706, O43917, Q8TCX4, Q9BTB5
UniProt Entry Name MSH6_HUMAN
Gene Symbol MSH6
GeneID 2956
OMIM 114500
HGNC 7329
KEGG hsa:2956
Ensembl ENSG00000116062
String 9606.ENSP00000234420
Molecular Weight 160 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MSH6

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