Methylenetetrahydrofolate Reductase (MTHFR) Antibody
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Catalogue No: abx011720
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Research Articles on Methylenetetrahydrofolate Reductase (MTHFR)
| Target | Methylenetetrahydrofolate Reductase (MTHFR) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MTHFR expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P42898 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7A6, Q5SNW6, Q5SNW9, Q7Z6M6, Q8IU73, Q9UQR2 |
| UniProt Entry Name | MTHR_HUMAN |
| GeneID | 4524 |
| KEGG | hsa:4524 |
| String | 9606.ENSP00000365777 |
| Molecular Weight | 75 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |