MTOR (pS2448) Antibody

MTOR (pS2448) Antibody is a Rabbit Polyclonal antibody against MTOR (pS2448). The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Target	MTOR (pS2448)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around S2448 of human mTOR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42345 (UniProt, ExPASy)
UniProt Secondary AC	Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
UniProt Entry Name	MTOR_HUMAN
Gene Symbol	MTOR
GeneID	2475
NCBI Accession	NP_004949.1
KEGG	hsa:2475
String	9606.ENSP00000354558
Molecular Weight	Calculated MW: 289 kDa Observed MW: 289 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on MTOR (pS2448)

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