Mucin 20 (MUC20) Antibody
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Catalogue No: abx025134
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on Mucin 20 (MUC20)
| Target | Mucin 20 (MUC20) |
| Research Area | Tumor Immunity, Infection Immunity, Pulmonology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human MUC20. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8N307 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6UX97, Q76I83, Q76I85, Q86ST8, Q8NBY6, Q96KA1, Q9P2I8 |
| UniProt Entry Name | MUC20_HUMAN |
| Gene Symbol | MUC20 |
| GeneID | 200958 |
| OMIM | 610360 |
| NCBI Accession | NP_001269435.1 |
| HGNC | 23282 |
| KEGG | hsa:200958 |
| Ensembl | ENSG00000176945 |
| String | 9606.ENSP00000414350 |
| Molecular Weight | Calculated MW: 72 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |