Interferon-Induced GTP-Binding Protein Mx1 (MX1) Antibody

MX1 Antibody is a Rabbit Polyclonal antibody against MX1. Mx1 (also known as MxA) is a GTPase that belongs to the Mx family of proteins, which are ubiquitous in eukaryotes and involved in the immune response to viral infections. The human Mx1 is localized in the cytoplasm interfering with the translation of viral proteins, whereas the mouse Mx1 accumulates in the nucleus and inhibits the primary transcription of viral RNA. Mx1 expression is induced by treatment with α/β interferon (INF). This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.

Target	Interferon-Induced GTP-Binding Protein Mx1 (MX1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human MX1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20591 (UniProt, ExPASy)
UniProt Entry Name	MX1_HUMAN
Gene Symbol	MX1
GeneID	4599
NCBI Accession	NP_001171517.1
KEGG	hsa:4599
String	9606.ENSP00000381601
Molecular Weight	Calculated MW: 76 kDa Observed MW: 76 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interferon-Induced GTP-Binding Protein Mx1 (MX1)

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