MYC (pS373) Antibody

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Catalogue No: abx000184
Price: US$377.00
(Size: 50 µl)

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Datasheet SDS
MYC (pS373) Antibody is a Rabbit Polyclonal antibody against MYC (pS373). The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Target MYC (pS373)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A phospho specific peptide corresponding to residues surrounding S373 of human c-Myc
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01106 (UniProt, ExPASy)
UniProt Secondary AC A8WFE7, P01107, Q14026
UniProt Entry Name MYC_HUMAN
Gene Symbol MYC
GeneID 4609
KEGG hsa:4609
String 9606.ENSP00000479618
Molecular Weight Calculated MW: 51 kDa
Observed MW: 60 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MYC (pS373)


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