N-Myc Proto-Oncogene Protein (MYCN) Antibody

Catalogue No: abx000732
Price: £120.00
(Size: 20 µl)
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MYCN Antibody is a Rabbit Polyclonal antibody against MYCN. MYCN, also named as BHLHE37 and NMYC, is a transcription factor. It is primarily expressed in normal developing embryos and is thought to be critical in brain and other neural development. It is often amplified in human neuroblastomas. IR34A can suppress MYCN expression, it suggest MYCN has a role in cell growth. The expression of the MCYN is upregulated in a variety of human tumors, most requently neuroblastoma, where the level of expression appearts to increase as teh tumor progress.

Target MYCN
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MYCN.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04198 (UniProt, ExPASy)
UniProt Secondary AC Q53XS5, Q6LDT9
UniProt Entry Name MYCN_HUMAN
Gene Symbol MYCN
GeneID 4613
KEGG hsa:4613
String 9606.ENSP00000281043
Molecular Weight Calculated MW: 49 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MYCN

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