Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody
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Catalogue No: abx033978
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US$326.25
(Size: 50 µl)
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Datasheet SDS
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
Research Articles on Myeloid Differentiation Primary Response Protein MyD88 (MYD88)
| Target | Myeloid Differentiation Primary Response Protein MyD88 (MYD88) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Pulmonology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 136-164 amino acids from the Central region of human MyD88. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q99836 (UniProt, ExPASy) |
| UniProt Entry Name | MYD88_HUMAN |
| Gene Symbol | MYD88 |
| NCBI Accession | NP_001166037.1 NP_001166039.1 NP_001166040.1 NP_002459.2 |
| KEGG | hsa:4615 |
| String | 9606.ENSP00000401399 |
| Molecular Weight | Calculated MW: 33.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey MYD88. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |