Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody

Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody is a Rabbit Polyclonal antibody for the detection of MYD88.

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Target	Myeloid Differentiation Primary Response Protein MyD88 (MYD88)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	myeloid differentiation primary response gene
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q99836 (UniProt, ExPASy)
UniProt Entry Name	MYD88_HUMAN
Gene Symbol	MYD88
GeneID	4615
OMIM	602170
HGNC	7562
KEGG	hsa:4615
Ensembl	ENSG00000172936
String	9606.ENSP00000401399
Molecular Weight	Observed MW: 33 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Myeloid Differentiation Primary Response Protein MyD88 (MYD88)

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