Myelin-Oligodendrocyte Glycoprotein (MOG) Protein

Myelin-Oligodendrocyte Glycoprotein (MOG) is a single, non-glycosylated polypeptide chain containing 21 amino acids. The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Target	Myelin-Oligodendrocyte Glycoprotein (Myelin-Oligodendrocyte Glycoprotein (MOG) Protein)
Research Area	Infection Immunity, Neuroscience, Genetics, Autoimmunity
Tested Applications	SDS-PAGE
Conjugation	Unconjugated
Form	Lyophilized
Activity	Not tested
Purity	> 97% (SDS-PAGE and RP-HPLC)
Reconstitution	It is recommended to reconstitute the lyophilized MOG in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage	Store at 4°C if entire vial will be used within 2-4 weeks. Store at -20°C for longer periods of time. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid repeated freeze/thaw cycles.
Molecular Weight	2581 Da
Molecular Formula	C118H177N35O29S
Sequence	H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH.
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Myelin-Oligodendrocyte Glycoprotein (Myelin-Oligodendrocyte Glycoprotein (MOG) Protein)

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