Histone H2A Deubiquitinase MYSM2 (MYSM1) Antibody
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Catalogue No: abx002231
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US$217.50
(Size: 20 µl)
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Datasheet SDS
MYSM1 Antibody is a Rabbit Polyclonal antibody against MYSM1. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Research Articles on Histone H2A Deubiquitinase MYSM2 (MYSM1)
| Target | Histone H2A Deubiquitinase MYSM2 (MYSM1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to MYSM1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q5VVJ2 (UniProt, ExPASy) |
| UniProt Secondary AC | A8KA54, B3KX65, Q68DD3, Q6AI53, Q7Z3G8, Q96PX3 |
| UniProt Entry Name | MYSM1_HUMAN |
| Gene Symbol | MYSM1 |
| GeneID | 114803 |
| NCBI Accession | NP_001078956.1 |
| KEGG | hsa:114803 |
| String | 9606.ENSP00000418734 |
| Molecular Weight | Calculated MW: 95 kDa Observed MW: 105 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |

