NGFI-A-Binding Protein 2 (NAB2) Antibody

NAB2 Antibody is a Rabbit Polyclonal antibody against NAB2. This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Target	NGFI-A-Binding Protein 2 (NAB2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human NAB2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15742 (UniProt, ExPASy)
UniProt Secondary AC	B2RAK3, O76006, Q14797
UniProt Entry Name	NAB2_HUMAN
Gene Symbol	NAB2
GeneID	4665
NCBI Accession	NP_005958.1
KEGG	hsa:4665
String	9606.ENSP00000300131
Molecular Weight	Calculated MW: 57 kDa Observed MW: 70 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	2.31 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NGFI-A-Binding Protein 2 (NAB2)

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