NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) Antibody
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Catalogue No: abx027185
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Research Articles on NEDD8 Activating Enzyme E1 Subunit 1 (NAE1)
| Target | NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 172-200 amino acids from the Central region of human NAE1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13564 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NCK0, A6NFN4, A8MU28, B2R700, B3KUP9 |
| UniProt Entry Name | ULA1_HUMAN |
| KEGG | hsa:8883 |
| String | 9606.ENSP00000351990 |
| Molecular Weight | Calculated MW: 60.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Monkey NAE1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |