+44 (0) 1223 755950
+1 832 327 7413
Nicotinamide Phosphoribosyltransferase (NAMPT) Antibody
REQUEST MORE INFO
Catalogue No: abx000641
Price:
US$203.00
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Nicotinamide Phosphoribosyltransferase (NAMPT) Antibody is a Rabbit Polyclonal antibody against Nicotinamide Phosphoribosyltransferase (NAMPT). Nicotinamide Phosphoribosyltransferase (NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus (T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.
Research Articles on Nicotinamide Phosphoribosyltransferase (NAMPT)
| Target | Nicotinamide Phosphoribosyltransferase (NAMPT) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 181-382 of human PBEF/Visfatin/NAMPT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P43490 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D0Q9, A4D0R0, Q3KQV0, Q8WW95 |
| UniProt Entry Name | NAMPT_HUMAN |
| Gene Symbol | NAMPT |
| GeneID | 10135 |
| NCBI Accession | NP_005737.1 |
| KEGG | hsa:10135 |
| String | 9606.ENSP00000222553 |
| Molecular Weight | Calculated MW: 56 kDa Observed MW: 56 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
