Homeobox Protein NANOG (NANOG) Antibody
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Catalogue No: abx011232
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US$427.75
(Size: 100 µl)
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Datasheet SDS
NANOG: Nanog homeobox. Entrez Protein NP079141. Nanog is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Human Nanog protein shares 52% overall amino acid identity with the mouse protein and 85% identity in the homeodomain. Human Nanog maps to gene locus 12p13.31, whereas mouse Nanog maps to gene loci 6 F2. Murine embryonic Nanog expression is detected in the inner cell mass of the blastocyst. High levels of human Nanog expression were detected by Northern analysis in the undifferentiated N-Tera embryonal carcinoma cell line.
Research Articles on Homeobox Protein NANOG (NANOG)
| Target | Homeobox Protein NANOG (NANOG) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of NANOG (aa20-166) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9H9S0 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DUU4, Q2TTG0, Q6JZS5 |
| UniProt Entry Name | NANOG_HUMAN |
| Gene Symbol | NANOG |
| GeneID | 79923 |
| OMIM | 607937 |
| HGNC | 20857 |
| Ensembl | ENSG00000111704 |
| String | 9606.ENSP00000229307 |
| Molecular Weight | 35 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |