Natriuretic Peptides B (NPPB) Antibody

Catalogue No: abx001791
Price: £120.00
(Size: 20 µl)
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NPPB Antibody is a Rabbit Polyclonal antibody against NPPB. This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.

Target Natriuretic Peptides B (NPPB)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human NPPB.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16860 (UniProt, ExPASy)
UniProt Secondary AC B0ZBE9, Q6FGY0, Q9P2Q7
UniProt Entry Name ANFB_HUMAN
Gene Symbol NPPB
GeneID 4879
NCBI Accession NP_002512.1
KEGG hsa:4879
String 9606.ENSP00000365651
Molecular Weight Calculated MW: 14 kDa
Observed MW: 14 kDa
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Concentration 2.48 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Natriuretic Peptides B (NPPB)

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