Next To BRCA1 Gene 1 Protein (NBR1) Antibody

NBR1 Antibody is a Rabbit Polyclonal antibody against NBR1. The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene.

Target	Next To BRCA1 Gene 1 Protein (NBR1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human NBR1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14596 (UniProt, ExPASy)
UniProt Secondary AC	Q13173, Q15026, Q5J7Q8, Q96GB6, Q9NRF7
UniProt Entry Name	NBR1_HUMAN
Gene Symbol	NBR1
GeneID	4077
NCBI Accession	NP_005890.2
KEGG	hsa:4077
String	9606.ENSP00000411250
Molecular Weight	Calculated MW: 107 kDa Observed MW: 120 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Next To BRCA1 Gene 1 Protein (NBR1)

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