Neutrophil Cytosolic Factor 2 (NCF2) Antibody

NCF2 Antibody is a Rabbit Polyclonal antibody against NCF2. This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Neutrophil Cytosolic Factor 2 (NCF2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 227-526 of human NOXA2/p67phox.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P19878 (UniProt, ExPASy)
UniProt Entry Name	NCF2_HUMAN
Gene Symbol	NCF2
GeneID	4688
NCBI Accession	NP_000424.2
KEGG	hsa:4688
String	9606.ENSP00000356505
Molecular Weight	Calculated MW: 60 kDa Observed MW: 68 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Neutrophil Cytosolic Factor 2 (NCF2)

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